SSM Health Medical Group
Matthew Johnson, MD
Radiation Oncology

Dr. Matthew Johnson is a board-certified radiation oncologist who provides comprehensive care for patients ages 18 and older. He brings advanced training in cutting-edge technologies and image-guided therapies, with expertise in 3D-conformal radiation therapy (3D-CRT), intensity modulated radiation therapy (IMRT), image-guided radiotherapy (IGRT), stereotactic body radiotherapy (SBRT), stereotactic radiosurgery (SRS), and brachytherapy. His clinical focus includes cancers of the breast, lung, prostate, gastrointestinal tract, head and neck, as well as lymphoma.
Dr. Johnson is deeply committed to patient education, striving to make complex diagnoses and treatment options understandable and approachable. He prioritizes building meaningful relationships with his patients and delivers personalized, evidence-based care that reflects both compassion and clinical excellence.
He is affiliated with the American Society for Radiation Oncology and the American Brachytherapy Society. His honors include the Lynn Sage Breast Cancer Achievement Award, the American Radium Society Young Oncologist Award, and recognition as a Castle Connolly "Top Doctor" and St. Louis Magazine "Best Doctor." He frequently presents at international oncology conferences and has co-authored research published in leading journals such as JCO, JAMA, JNCCN, and Practical Radiation Oncology.
Having personally undergone radiation treatment for cancer during medical school, Dr. Johnson brings a unique perspective and empathy to his practice. Outside of medicine, he enjoys spending time with family, mountain biking, photography, SCUBA diving, traveling, and woodworking.
Dr. Johnson is deeply committed to patient education, striving to make complex diagnoses and treatment options understandable and approachable. He prioritizes building meaningful relationships with his patients and delivers personalized, evidence-based care that reflects both compassion and clinical excellence.
He is affiliated with the American Society for Radiation Oncology and the American Brachytherapy Society. His honors include the Lynn Sage Breast Cancer Achievement Award, the American Radium Society Young Oncologist Award, and recognition as a Castle Connolly "Top Doctor" and St. Louis Magazine "Best Doctor." He frequently presents at international oncology conferences and has co-authored research published in leading journals such as JCO, JAMA, JNCCN, and Practical Radiation Oncology.
Having personally undergone radiation treatment for cancer during medical school, Dr. Johnson brings a unique perspective and empathy to his practice. Outside of medicine, he enjoys spending time with family, mountain biking, photography, SCUBA diving, traveling, and woodworking.
About Me
Specialties
Radiation Oncology
Gender
Male
Education
Mercy Hospital St. Louis
Internship, 2011
Fox Chase Cancer Center
Residency, 2015
University of Missouri - Columbia School of Medicine
Medical School, 2010
Hospital Affiliations
SSM Health DePaul Hospital - St. Louis
SSM Health St. Clare Hospital - Fenton
SSM Health St. Joseph Hospital - Lake Saint Louis
SSM Health St. Joseph Hospital - St. Charles
SSM Health St. Mary's Hospital - St. Louis
Certifications
Drug Enforcement Administration
Missouri Dept of Health/Narcotics&Dangerous Drugs
Missouri State Board of Registration
Medical Interests
Breast cancer
Gastrointestinal cancers
Lung cancer
Prostate cancer
Reviews
Rating Breakdown
Reviews are measured on a scale of 1 to 5, with 5 being the best score.
Question Breakdown
5.0Overall Experience5.0Listened Carefully4.9Explained Things Clearly4.9Knew Medical History5.0Involved in Care Decisions5.0Showed Courtesy & Respect
Patient Reviews
SSM Health only displays patient satisfaction data for providers included in our survey process and who have a minimum of 30 returned surveys. The overall rating is an average of all responses to the survey questions listed below. The ratings and comments submitted by patients reflect their own views and opinions. Patient identities are withheld to ensure confidentiality and privacy. Learn more about our survey.
5 out of 5
113 ratings,
51 reviews
7/22/2026
Fantastic doc and staff
7/15/2026
He takes the time to answer all questions and explains everything that is being done.
7/14/2026
Cares about the patient and their cancer journey
7/10/2026
He is the BEST! Thank you for saving my life!
7/5/2026
Great guy, put your mind at ease. During Uncertain times
Map & Directions
SSM Health Cancer Care
1475 Kisker RoadSt. Charles, MO 63304
Mon
8:30 am - 4:30 pm
Tue
8:30 am - 4:30 pm
Wed
8:30 am - 4:30 pm
Thu
8:30 am - 4:30 pm
Fri
8:30 am - 4:30 pm
Sat
Closed
Sun
Closed
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