Jesse "Dwayne" Helton, DO is a board-certified internal medicine physician who cares for adults ages 18 and older throughout the St. Louis metropolitan area. Dr. Helton offers comprehensive primary care with a focus on treating the whole person and supporting long-term wellness. He provides services such as joint injections, minor skin and nail procedures, and osteopathic manipulation to help patients manage pain and improve mobility.

Dr. Helton has special medical interests in wellness and wholistic care, as well as nephrology, rheumatology, geriatrics, and natural remedies. He is committed to providing compassionate, ethical, and evidence‑based care. He takes time to listen closely, understand each patient's values and life experiences, and work alongside them to create individualized, sustainable treatment plans. His approach is guided by lifelong learning and a dedication to healing, prevention, and overall wellbeing.

He is a member of the American Osteopathic Association and the American Board of Osteopathic Internists.

Outside of medicine, Dr. Helton and his family enjoy living close to nature. They operate a small farm where they garden and raise chickens, miniature cattle, miniature goats, and miniature hogs.